Part 1: Visualizing and Controlling Molecules for Life.- Chapter 1. Photoacoustic Tomography: Deep Tissue Imaging by Ultrasonically Beating Optical Diffusion.- Chapter 2. Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions.- Chapter 3. Eavesdropping on Biological Processes with Multi-Dimensional Molecular Imaging.- Chapter 4. Apical microtubules define the function of epithelial cell sheets consisting of non-ciliated or multi-ciliated cells.- Chapter 5. Illuminating the brain.- Chapter 6. Optogenetic assemblies of cortical force-generating complexes during mitosis.- Chapter 7. In vivo Imaging Probes with Tunable Chemical Switches.- Chapter 8. Circuit-dependent striatal PKA and ERK signaling underlying action selection.- Chapter 9. Electrophysiology, Unplugged: New Chemical Tools to Image Voltage.- Chapter 10. Molecular dynamics revealed by single-molecule FRET measurement.- Chapter 11. Comprehensive approaches using luminescence to studies of cellular functions.- Part II: Imaging Disease Mechanisms.- Chapter 12. Make Chronic Pain Visible.- Chapter 13. Cortical plasticity after spinal cord injury using resting-state functional magnetic resonance imaging.- Chapter 14. Multimodal Label-free imaging to assess compositional and morphological changes in cells during immune activation.- Chapter 15. Investigating in vivo myocardial and coronary molecular pathophysiology in mice with X-ray radiation imaging approaches.- Chapter 16. Visualizing the Immune Response to Infections.- Chapter 17. Imaging Sleep and Wakefulness.- Chapter 18. Abnormal local translation in dendrites impairs cognitive functions in neuropsychiatric disorders.- Chapter 19. Imaging synapse formation and remodeling in vitro and in vivo.- Part III: Imaging-based Diagnosis and Therapy.- Chapter 20. How MRI makes the Brain Visible.- Chapter 21. Intravital multiphoton imaging revealing cellular dynamics in vivo.- Chapter 22. Theranostic Near Infrared Photoimmunotherapy for Cancer.- Chapter 23. Novel and integrated imaging on Chronic Fatigue.- Chapter 24. Novel fluorescent probes for rapid tumor imaging and fast glutathione dynamics.- Chapter 25. Coronary Heart Disease Diagnosis: Engineering Triumphs, Economic Barriers.- Chapter 26. Live imaging of the skin immune responses.- Chapter 27. Development of a horizontal CT and its application to musculoskeletal disease.- Chapter 28. The Future of Precision Health & Integrated Diagnostics.- Chapter 29. Imaging and therapy against hypoxic tumors with 64Cu-ATSM.