Part I Ultrasound Imaging: 1 Ultrasound Features of Thyroid, Parathyroid, Neck Lymph Nodes: Normal and Pathologic Pattern.- 2 Fine needle aspiration biopsy. - 3 Cytology of Thyroid Lesions.- 4 Molecular Markers in Thyroid Fine Needle Aspiration Biopsies. Part II Ultrasound-guided Interventional Techniques: 5 Percutaneous Ethanol Injection for the management of Thyroid Lesions.- 6 Percutaneous Laser Thermal Ablation (LAT).-7 Percutaneous Radiofrequency Thermal Ablation (RFA).- 8 High-intensity Focused Ultrasound Ablation (HI-FU) in Endocrine Neck Diseases.- 9 Mini-invasive Techniques for the Treatment of Thyroid Nodules: critical issues.- Part III Minimally Invasive Surgical Techniques: 10 Minimally Invasive Video-Assisted Thyroidectomy (MIVAT).- 11 Locoregional anesthesia in thyroid and parathyroid surgery.- 12 Robotic Thyroidectomy.- 13 Minimally Invasive Video-Assisted Parathyroidectomy (MIVAP).- 14 Endoscopic Parathyroidectomy.- 15Minimally Invasive Video-Assisted Neck Dissection.- 16 Minimally Invasive Surgical Techniques: Critical Appraisal and Future Perspectives.- Part IV Intraoperative Adjuncts: 17 EBLSN Intraoperative Nerve Monitoring.- 18 Recurrent Laryngeal Nerve Monitoring.- 19 Hemostatic device.- 20 Hemostatic agents.- 21 Critical Appraisal of Intraoperative adjuncts.- Part V: Key-Points.- 22 How to Avoid and Manage Post-operative Complications.- 23 Peri-Operative Medical Treatment.- 24 Patient Counseling and Patients Involvement in Health Policy.