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Virus as Populations
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Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere.
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Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere.
Produktdetaljer
Sprog: Engelsk
Sider: 428
ISBN-13: 9780128008379
Indbinding: Paperback
Udgave:
ISBN-10: 0128008377
Udg. Dato: 14 okt 2015
Længde: 23mm
Bredde: 195mm
Højde: 236mm
Oplagsdato: 14 okt 2015
Forfatter(e) Esteban (Centro de Biologia Molecular Severo Ochoa Domingo, Esteban Domingo


Kategori Smitsomme sygdomme. Infektioner


Sprog Engelsk


Indbinding Paperback


Sider 428


Udgave


Længde 23mm


Bredde 195mm


Højde 236mm

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