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Mechanistic Toxicology
Af: Urs A. Boelsterli, Urs Boelsterli Engelsk Paperback
SPAR
kr 156
Mechanistic Toxicology
Af: Urs A. Boelsterli, Urs Boelsterli Engelsk Paperback
A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology.

Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity.

New in the Second Edition

  • Updated chapters
  • Types of toxic responses
  • Disruption of signal transduction by xenobiotics
  • Disruption of mitochondrial function
  • Novel mechanisms derived from systems toxicology
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    A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology.

    Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity.

    New in the Second Edition

  • Updated chapters
  • Types of toxic responses
  • Disruption of signal transduction by xenobiotics
  • Disruption of mitochondrial function
  • Novel mechanisms derived from systems toxicology
  • Se mere i:
    Produktdetaljer
    Sprog: Engelsk
    Sider: 416
    ISBN-13: 9780849372728
    Indbinding: Paperback
    Udgave:
    ISBN-10: 0849372720
    Kategori: Biokemi
    Udg. Dato: 23 mar 2007
    Længde: 5mm
    Bredde: 292mm
    Højde: 216mm
    Oplagsdato: 23 mar 2007
    Forfatter(e) Urs A. Boelsterli, Urs Boelsterli


    Kategori Biokemi


    Sprog Engelsk


    Indbinding Paperback


    Sider 416


    Udgave


    Længde 5mm


    Bredde 292mm


    Højde 216mm


    Udg. Dato 23 mar 2007


    Oplagsdato 23 mar 2007

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